Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes
نویسندگان
چکیده
منابع مشابه
Activation-associated secreted proteins are the most abundant antigens in a host protective fraction from Ostertagia ostertagi.
P. Geldhof a,∗, I. Vercauteren a, K. Gevaert b, A. Staes b, D.P. Knox c, J. Vandekerckhove b, J. Vercruysse a, E. Claerebout a a Laboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke B9820, Belgium b Department of Medical Protein Research, Flanders Interuniversity Institute for Biotechnology, Ghent University, Merelbeke, Belgium c Moredun Res...
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The abomasal nematode Ostertagia ostertagi is a major causal agent contributing to production inefficiencies in the cattle industry in temperate regions of the world. Protective immunity to infections develops very slowly and resistance to reinfection manifests only after prolonged exposure. Mechanisms underlying the development of protective immunity remain largely unexplored. Immune animals, ...
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Reverse transcriptase-PCR (RT-PCR) was carried out on total RNA prepared from the third-stage larvae (L3) of Ostertagia ostertagi in order to clone and characterize the major transcripts expressed in this larval stage, as an initial investigation of arrested larval development in the parasite. Distinct bands were visible on an agarose gel and four of these were cloned and sequenced. Three of th...
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Recent reports of suspected ivermectin (IVM) resistance in Ostertagia ostertagi have highlighted the need for research into the mechanisms of IVM resistance. However, there are no reports of resistant field isolates of O. ostertagi, which have been characterized for molecular research. Therefore, an anthelmintic susceptible O. ostertagi population was selected for IVM resistance by repeatedly e...
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The mucus-dwelling parasite Ostertagia ostertagi is one of the most important gastrointestinal nematodes in cattle. Our group has previously demonstrated the protective capacity of a vaccine against this parasite based on a native activation-associated secreted protein ASP1 (nASP) in combination with the saponin adjuvant QuilA. The aim of the current study was to analyse the effect of both anti...
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ژورنال
عنوان ژورنال: Parasitology
سال: 2002
ISSN: 0031-1820,1469-8161
DOI: 10.1017/s0031182002002196